This visualization algorithm uses a density estimation approach based
on averaged shifted histograms [1]. In the one-dimensional
case, this method works by averaging
histograms with the same
bin width
, but with the origin of each histogram shifted by
from the previous histogram. In the multidimensional case, there are
multidimensional histograms averaged in total, i.e., for
shifts in each of the
dimensions. In our implementation,
the width of the histogram bin is determined as
, where
is the pixel size of the super-resolution image. The number of shifts
in the lateral and axial directions can be specified independently.